Successful treatment of idiopathic
hypersomnia and narcolepsy with modafinil.
Bastuji H; Jouvet M
Neurophysiologie Clinique,
Hospital Neurologique, Lyon, France
Prog Neuropsychopharmacol Biol Psychiatry, 12(5):695-700 1988
Abstract:
1. Modafinil, a putative central alpha 1
adrenergic agonist, was tested in idiopathic hypersomnia and narcolepsy.
2. Sleep attacks and drowsiness were
significantly decreased in 83% of 18 hypersomniac subjects and 71% of 24
narcoleptics.
3. When cataplectic episodes were not totally
suppressed the association of a low dose of Clomipramine was successful in
improving them.
4. Modafinil, used for at least 3 years in some
patients, produces, in most cases, no peripheric sides effects, does not disturb
night sleep and is never responsible of tolerance of drug dependence.
HOME
to
order
1. Modafinil augmentation
of antidepressant treatment
2. Modafinil children
with attention-deficit/hyperactivity disorder
3. Modafinil in
fibromyalgia treatment
4. Modafinil
efficacy in narcolepsy
5. Modafinil narcolepsy:
symptoms and management
6. Modafinil successful
treatment of hypersomnia & narcolepsy
7. Modafinil
drug of choice for narcolepsy
8. Modafinil
in the treatment of
narcolepsy
9. Modafinil
effect on narcolepsy
10. Modafinil
a narcolepsy study
11. Modafinil
switching from narcolepsy drugs to modafinil
12. Modafinil
and naps as counter measures in sleep deprivation
13. Modafinil
as a treatment for excessive daytime sleepiness
14. Modafinil
use in a sleep deprivation experiment
15. Modafinil excessive sleepiness in Parkinson's disease
16. Modafinil the
unique properties of a new stimulant
17. Modafinil for
sustaining the alertness of helicopter pilots
18. Modafinil dosage
and safety
19. Modafinil
treatment of alcoholic organic brain syndrome
20. Modafinil
effect on melatonin, cortisol, and growth hormone
21. Modafinil
in obstructive sleep apnea-hypopnea syndrome
22. Modafinil
vs dextroamphetamine in treatment of adult ADHD
23. Modafinil
dopaminergic transmission mediates CNS stimulants
24. Modafinil
for daytime sleepiness in sleep apnea
25. Modafinil
treatment of residual excessive daytime sleepiness
26. Modafinil
amplification of cortical serotonin release
27. Modafinil for the treatment of
multiple sclerosis
